Meiosis is the process by which diploid germ cells divide to produce haploid gametes for sexual reproduction. The process is highly conserved in eukaryotes, however the recent availability of mouse models for meiotic recombination has revealed surprising regulatory differences between simple unicellular organisms and those with increasingly complex genomes. Moreover, in these higher eukaryotes, the intervention of physiological and sex-specific factors may also influence how meiotic recombination and progression are monitored and regulated. This review will focus on the recent studies (...) involving mouse mutants for meiosis, and will highlight important differences between traditional model systems for meiosis (such as yeast) and those involving more complex cellular, physiological and genetic criteria. BioEssays 23:996–1009, 2001. © 2001 John Wiley & Sons, Inc. (shrink)

§ 1. The dates for Peisistratus’ reigns and exiles in the Athenaion Politeia, as given in the papyrus, which is the sole authority for the text, are as follows.

In consulatu sexto et septimo postquam bella civilia exstinxeram per consensum universorum [potitus rerum own]ium rem publicam ex mea potestate in senat[us populique Romani a]rbitrium transtuli. There is very little doubt about the reading of the Latin text, except that the Greek has suggested to Schönbauer that ‘compos’ should be read for ‘potitus’. He urges that ‘compos’ has a ‘milder meaning’ than ‘potitus’ and has no connotation of the use of force. The change to ‘compos’ is worthy of consideration, but (...) suggests that the Latin ran ‘compos factus’ if ‘compos’ was used, and the phrase ‘compos factus’, though good Augustan Latin, is perhaps too retarding in rhythm to fit this place, though to that stylistic feeling too much weight should not be assigned. (shrink)

It may be affirmed with some confidence that on this topic no generally accepted solution will be found in default of new evidence, for which we can only faintly hope. Against certainty on the matter it would seem that the Everlasting has fixed his canon: quis iustius induit arma scire nefas. Dogmatism is out of place; we must be content with whatever theory is least difficult to reconcile with the texts and with a reasonable interpretation of the course of events (...) at the time and the comments on them of contemporary observers. The thesis advanced in this paper is that there are strong reasons for supposing that the Lex Pompeia Licinia contained a date by which Caesar's command ended, that this date was not the end of February of the year 50 or the year 49 or the end of December of the year 50, that it did not contain a clause forbidding the discussion of a successor to Caesar before March 1, 50, and that if the date ending his command lies between the end of February and the end of December of the year 50, it may have been in fact the Ides of November in that year. (shrink)

The encounter between Socrates and Thrasymachus in Republic I is notoriously baffling. Most of what is said seems straightforward, and the issues at stake are ones of common concern, but the argument remains elusive. The purpose of this paper is to investigate the nature and grounds of this elusiveness, and to show that some of it can be dispelled by a sufficiently free-ranging exegesis that bears in mind the general character of Plato’s writing.